44 Additionally, anergic cells Commonly retain a better susceptibility to apoptosis Except if anti-apoptotic proteins such as BCL2 are overexpressed, as is the case for CLL cells.forty five Without a doubt, most major therapeutic improvements happening in the last decade are linked to the inhibition of BCR and BCL2-mediated signaling. https://bobbyu864xrl6.bloggip.com/profile