Epidural clonidine applied as an adjunct to local anesthetics has 3 distinct mechanisms of action. 1st, the stimulation of alpha-2-receptors while in the dorsal horn minimizes soreness transmission. Next, clonidine could potentially cause regional vasoconstriction that boundaries vascular removal of local epidural anesthetics. Applies to clonidine: oral tablet, oral https://express-page.com/story5138421/everything-about-onolidine